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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRSK1
All Species:
11.21
Human Site:
S458
Identified Species:
24.67
UniProt:
Q8TDC3
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDC3
NP_115806.1
794
86753
S458
G
A
S
T
G
L
S
S
S
P
L
S
S
P
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_541413
801
87720
S465
G
A
S
T
G
L
S
S
S
P
L
S
S
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q5RJI5
778
85136
S442
G
A
S
T
G
L
S
S
S
P
L
S
S
P
R
Rat
Rattus norvegicus
O08679
722
80853
A388
A
D
L
T
N
S
S
A
P
S
P
S
H
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514667
306
34673
Chicken
Gallus gallus
Q9IA88
798
88848
E440
I
S
P
S
S
L
L
E
T
T
I
S
E
E
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
P556
K
R
P
R
G
Q
S
P
L
V
T
S
P
H
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648814
861
95238
P431
R
S
S
S
Y
H
S
P
T
R
C
N
S
P
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9TW45
1192
126331
S584
S
S
S
S
R
R
S
S
Q
N
D
A
A
A
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38997
535
61163
P203
L
K
T
S
C
G
S
P
N
Y
A
A
P
E
V
Baker's Yeast
Sacchar. cerevisiae
P34244
1518
169574
E562
E
S
D
K
A
E
A
E
A
V
T
L
P
P
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
98.1
N.A.
94.8
29.2
N.A.
32.1
28.3
N.A.
25.1
N.A.
48.5
N.A.
25.7
N.A.
Protein Similarity:
100
N.A.
N.A.
98.2
N.A.
95.4
44.5
N.A.
33.3
43.9
N.A.
38.5
N.A.
62.5
N.A.
37.9
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
20
N.A.
0
13.3
N.A.
20
N.A.
26.6
N.A.
20
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
26.6
N.A.
0
40
N.A.
20
N.A.
53.3
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
27
22.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.9
34.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
28
0
0
10
0
10
10
10
0
10
19
10
10
10
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
10
10
0
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
10
0
0
0
0
10
0
19
0
0
0
0
10
19
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
28
0
0
0
37
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
10
10
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
10
10
0
10
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
10
0
10
0
0
37
10
0
10
0
28
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
10
0
0
0
10
10
0
10
0
0
0
% N
% Pro:
0
0
19
0
0
0
0
28
10
28
10
0
28
46
10
% P
% Gln:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% Q
% Arg:
10
10
0
10
10
10
0
0
0
10
0
0
0
0
28
% R
% Ser:
10
37
46
37
10
10
73
37
28
10
0
55
37
0
0
% S
% Thr:
0
0
10
37
0
0
0
0
19
10
19
0
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
19
0
0
0
0
28
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _